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MOTS-c 10mg

MOTS-c 10mg

MOTS-c is a synthetic mitochondrial-derived peptide supplied in lyophilised
powder format for laboratory and analytical research applications. It is
commonly utilised within controlled research environments investigating
mitochondrial signalling, metabolic regulation and intracellular
communication pathways.

This peptide is studied in biochemical and cellular research systems focused
on energy metabolism, adaptive stress signalling and mitochondrial–nuclear
interactions under controlled laboratory conditions.

Product Details

  • Product Name: MOTS-c
  • Synonyms: Mitochondrial ORF of the Twelve S rRNA-c
  • CAS Number: 1627580-64-6
  • Molecular Formula: C101H152N28O22S2
  • Molecular Weight: ~2174.64 g/mol
  • Peptide Length: 16 amino acids
  • Peptide Type: Mitochondrial-derived regulatory peptide
  • Purity: ≥ 99% HPLC typical
  • Appearance: White to off-white lyophilised powder
  • Pack Size: 10mg
  • Storage: Desiccated, protected from light, stored at –20°C or below
  • Solubility: Soluble in water and buffered aqueous solutions

Description & Research Context

MOTS-c corresponds to a naturally occurring mitochondrial-derived peptide
encoded within the mitochondrial 12S rRNA region. In research environments,
it is commonly utilised to investigate mitochondrial signalling pathways,
metabolic regulation mechanisms and nuclear–mitochondrial communication.

Experimental models have examined the influence of MOTS-c on intracellular
signalling pathways associated with energy sensing, insulin signalling and
adaptive cellular stress responses. Research applications frequently focus on
AMPK activation, metabolic gene expression and peptide-mediated stress
signalling under controlled laboratory conditions.

Observed molecular responses may vary depending on peptide concentration,
exposure duration, metabolic state and experimental model design.

Applications in Research

  • Study of mitochondrial-derived peptide signalling pathways
  • Investigation of metabolic regulation and energy homeostasis mechanisms
  • In vitro analysis of mitochondrial–nuclear communication
  • Research into AMPK activation and metabolic gene expression
  • Use as a reference compound in mitochondrial biology and metabolism research

Handling, Reconstitution & Stability

  • Weigh under dry laboratory conditions, as peptides may be hygroscopic
  • Reconstitute using sterile water or appropriate buffered aqueous solutions
  • Avoid vigorous agitation during dissolution
  • Filter sterilise if required prior to laboratory use
  • Aliquot and store reconstituted solutions at –20°C or lower
  • Avoid repeated freeze-thaw cycles

Precautions & Notes

Experimental behaviour of MOTS-c may vary depending on metabolic state,
cellular model, peptide concentration and exposure duration. Buffer
composition, pH and ionic strength may influence peptide stability and assay
performance during laboratory procedures.

Appropriate laboratory controls are recommended to distinguish
peptide-specific signalling activity from non-specific experimental effects.

Research Use Only

This product is supplied strictly for laboratory, analytical and scientific
research purposes only. It is not intended for human consumption, veterinary
use, therapeutic use, diagnostic use, medical use, cosmetic use, food use or
recreational use.

£90.00

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Product Specifications

Product Name MOTS-c 10mg
Size 500ml
Format vial
Intended Use research only
Storage firdge

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All Zineca products are supplied strictly for laboratory, analytical and research purposes only. They are not intended for human consumption, veterinary use, therapeutic use, diagnostic use, medical use or cosmetic use.

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